The effects of 528 Hz Music on the Endocrine and Autonomic Nervous Systems

It is well known that listening to music reduces stress. The group of scientists has investigated many aspects of this phenomenon, and it is recognized that several constituent elements of music are involved in this stress reduction effect.

This research and study was done by Akimoto, K., Hu, A.L., Yamaguchi, T. and Kobayashi, H.

The scientists examined the stress reduction effect of music with a frequency of 528 Hz by measuring its influence on the endocrine system and autonomic nervous system.

The full name of this very interesting study is “Effect of 528 Hz Music on the Endocrine System and Autonomic Nervous System”.

Music of the aforementioned frequency (528 Hz) has lately attracted attention as “healing” music. Usually, the reference tone of tuning is 440 Hz, and this is the international standard frequency (we refer to this as 440 Hz music). In this musical scale, there is no 528 Hz note. However, setting the reference tone to 444 Hz means that 528 Hz is included in the musical scale. We refer to music that is tuned and composed in this way as 528 Hz music.

In general, this specific type of music using a scale including 528 Hz is called solfeggio frequency music.

Various effects have been ascribed to the solfeggio frequency, but none of these have any scientific basis. Accordingly, we examined the effect of such music compared to 440 Hz music.

In this study, the scientists measured salivary biomarkers of stress (cortisol, chromogranin A, and oxytocin), which can be collected noninvasively, as indices of stress relief.

It is known that listening to music affects the endocrine system and autonomic nervous system. In the endocrine system, cortisol and chromogranin A have been used as indicators of stress. In a previous study, conducted in patients who had just undergone the stressful experience of learning in detail about the procedures involved in surgery that they would undergo the next day, salivary cortisol was significantly reduced among a group who listened to music for one hour, com-pared to a group who did not.

Additionally, in another study, which administered the Trier Social Stress Test (in which stress is caused to participants and their salivary cortisol levels thereby raised), the increase of salivary cortisol in a group who took the test while listening to relaxing music was significantly sup-pressed compared to that of a control group.

The 528 Hz music that was used in this study was soothing piano music.

This study offers a new piece of evidence for use in music therapy.